CIRCULAR RNA CIRCSFMBT2 DOWNREGULATION BY HBX PROMOTES HEPATOCELLULAR CARCINOMA METASTASIS VIA THE MIR-665/TIMP3 AXIS

Circular RNA circSFMBT2 downregulation by HBx promotes hepatocellular carcinoma metastasis via the miR-665/TIMP3 axis

Hepatitis B virus X protein (HBx) is considered as an oncogene in tumorigenesis and progression of hepatocellular carcinoma (HCC).In recent years, the important role of circular RNAs (circRNAs) in HCC has been increasingly demonstrated.However, the regulatory mechanisms of HBx on circRNAs remains largely unknown.In this study, we identified that a

read more



Slow complexification

The fact that AdS black hole interior geometries are time-dependent presents two challenges: first, to holographic duality (the boundary matter tends to equilibrate, often very quickly), and, second, to the idea that wormholes can be traversable (the wormhole geometry Cleaners and Solutions - Instrument Solutions is dynamic, and the wormhole is apt

read more